The undetectable specific antibody response in MIT-T-COVID-immunized mice demonstrates specific T cell responses alone can effectively attenuate the pathogenesis of SARS-CoV-2 infection. Our results suggest further study is merited for pan-variant T cell vaccines, including for individuals that cannot produce neutralizing antibodies or to help mitigate Long COVID.<\/p>\n<\/blockquote>\n

It\u2019s a promising line of inquiry and a great way to employ advances in computation in service of global health. But it\u2019s also important to recognize it is still early days for the \u201cpan-variant\u201d option. For one thing, it may work with or against existing vaccines \u2014 what if the best peptides for the immune response vaccine are the ones targeted for destruction by mRNA priming? The two would be working at cross purposes. And too strong an immune response also runs the risk of collateral damage, mistaken culling of ambiguously signaling cells and the like.<\/p>\n

But these are the good kind of questions \u2014 ones that are relevant because the basic function of the new vaccine appears to work. We\u2019ll know more as the team progresses through more tests of this promising approach.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

A new approach to vaccines with a machine learning twist could put an end to boosters and seasonal variant shots, according to MIT researchers. This \u201cpan-variant\u201d vaccine would ignore the virus itself but quickly control infections by cracking down on infected cells. To be quite clear, this is still in animal testing and is nowhere […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","om_disable_all_campaigns":false,"pagelayer_contact_templates":[],"_pagelayer_content":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[26,17,8],"tags":[],"class_list":["post-25703","post","type-post","status-publish","format-standard","hentry","category-science","category-tech","category-technology"],"yoast_head":"\n