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action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home4/scienrds/scienceandnerds/wp-includes/functions.php on line 6114Source:https:\/\/www.quantamagazine.org\/a-new-theory-for-the-assembly-of-life-in-the-universe-20230504\/#comments<\/a><\/br> Assembly theory predicts that objects like us can\u2019t arise in isolation \u2014 that some complex objects can only occur in conjunction with others. This makes intuitive sense; the universe could never produce just a single human. To make any humans at all, it had to make a whole bunch of us.<\/p>\n In accounting for specific, actual entities like humans in general (and you and me in particular), traditional physics is only of so much use. It provides the laws of nature, and assumes that specific outcomes are the result of specific initial conditions. In this view, we must have been somehow encoded in the first moments of the universe. But it surely requires extremely fine-tuned initial conditions to make Homo sapiens<\/em> (let alone you) inevitable.<\/p>\n Assembly theory, its advocates say, escapes from that kind of overdetermined picture. Here, the initial conditions don\u2019t matter much. Rather, the information needed to make specific objects like us wasn\u2019t there at the outset but accumulates in the unfolding process of cosmic evolution \u2014 it frees us from having to place all that responsibility on an impossibly fine-tuned Big Bang. The information \u201cis in the path,\u201d Walker said, \u201cnot the initial conditions.\u201d<\/p>\n Cronin and Walker aren\u2019t the only scientists attempting to explain how the keys to observed reality might not lie in universal laws but in the ways that some objects are assembled or transformed into others. The theoretical physicist Chiara Marletto<\/a> of the University of Oxford is developing a similar idea with the physicist David Deutsch. Their approach, which they call constructor theory<\/a> and which Marletto considers \u201cclose in spirit\u201d to assembly theory, considers which types of transformations are and are not possible.<\/p>\n \u201cConstructor theory talks about the universe of tasks able to make certain transformations,\u201d Cronin said. \u201cIt can be thought of as bounding what can happen within the laws of physics.\u201d Assembly theory, he says, adds time and history into that equation.<\/p>\n To explain why some objects get made but others don\u2019t, assembly theory identifies a nested hierarchy of four distinct \u201cuniverses.\u201d<\/p>\n In the Assembly Universe, all permutations of the basic building blocks are allowed. In the Assembly Possible, the laws of physics constrain these combinations, so only some objects are feasible. The Assembly Contingent then prunes the vast array of physically allowed objects by picking out those that can actually be assembled along possible paths. The fourth universe is the Assembly Observed, which includes just those assembly processes that have generated the specific objects we actually see.<\/p>\n Assembly theory explores the structure of all these universes, using ideas taken from the mathematical study of graphs<\/a>, or networks of interlinked nodes. It is \u201can objects-first theory,\u201d Walker said, where \u201cthe things [in the theory] are the objects that are actually made, not their components.\u201d<\/p>\n To understand how assembly processes operate within these notional universes, consider the problem of Darwinian evolution. Conventionally, evolution is something that \u201cjust happened\u201d once replicating molecules arose by chance \u2014 a view that risks being a tautology, because it seems to say that evolution started once evolvable molecules existed. Instead, advocates of both assembly and constructor theory are seeking \u201ca quantitative understanding of evolution rooted in physics,\u201d Marletto said.<\/p>\n According to assembly theory<\/a>, before Darwinian evolution can proceed, something has to select for multiple copies of high-AI objects from the Assembly Possible. Chemistry alone, Cronin said, might be capable of that \u2014 by narrowing down relatively complex molecules to a small subset. Ordinary chemical reactions already \u201cselect\u201d certain products out of all the possible permutations because they have faster reaction rates.<\/p>\n The specific conditions in the prebiotic environment, such as temperature or catalytic mineral surfaces, could thus have begun winnowing the pool of life\u2019s molecular precursors from among those in the Assembly Possible. According to assembly theory, these prebiotic preferences will be \u201cremembered\u201d in today\u2019s biological molecules: They encode their own history. Once Darwinian selection took over, it favored those objects that were better able to replicate themselves. In the process, this encoding of history became stronger still. That\u2019s precisely why scientists can use the molecular structures of proteins and DNA to make deductions about the evolutionary relationships of organisms.<\/p>\n Thus, assembly theory \u201cprovides a framework to unify descriptions of selection across physics and biology,\u201d Cronin, Walker and colleagues wrote<\/a>. \u201cThe \u2018more assembled\u2019 an object is, the more selection is required for it to come into existence.\u201d<\/p>\n \u201cWe\u2019re trying to make a theory that explains how life arises from chemistry,\u201d Cronin said, \u201cand doing it in a rigorous, empirically verifiable way.\u201d<\/p>\n<\/div>\n <\/br><\/br><\/br><\/p>\n
\nA New Idea for How to Assemble Life<\/br>
\n2023-05-08 21:58:09<\/br><\/p>\nShedding the Shackles of Determinism<\/strong><\/h2>\n