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{"id":3609,"date":"2022-04-14T11:00:08","date_gmt":"2022-04-14T11:00:08","guid":{"rendered":"https:\/\/scienceandnerds.com\/2022\/04\/14\/ancestry-will-tell-you-which-genetics-came-from-which-parent\/"},"modified":"2022-04-14T11:00:09","modified_gmt":"2022-04-14T11:00:09","slug":"ancestry-will-tell-you-which-genetics-came-from-which-parent","status":"publish","type":"post","link":"https:\/\/scienceandnerds.com\/2022\/04\/14\/ancestry-will-tell-you-which-genetics-came-from-which-parent\/","title":{"rendered":"Ancestry will tell you which genetics came from which parent"},"content":{"rendered":"

Source: https:\/\/www.theverge.com\/2022\/4\/13\/23021782\/ancestry-dna-sort-genes-parents-ethnicity<\/a>
\n
<\/br><\/code><\/p>\n

\n

Consumer genetics and genealogy company Ancestry announced a new feature, called SideView, that will give customers information about which bits of their DNA \u2014 and which parts of their ethnicity \u2014 were inherited from each parent. The tool can do that without having genetic information from the parents, which Ancestry says is a first in the industry.<\/p>\n

Separating out which parts of someone\u2019s genome came from which parent has been a challenge for researchers, says Barry Starr, the director of scientific communications at Ancestry. \u201cIt\u2019s a really big breakthrough for science in general,\u201d he told The Verge<\/em>. \u201cThat\u2019s really something that no one else has been able to do without having a parent tested as well.\u201d The feature will <\/strong>be automatically available for all users.<\/p>\n

Genetic information is packaged in pairs of chromosomes, and each parent contributes one copy of most chromosomes. DNA analysis, though, reads the sequence of genetic information without sorting out which half different sections came from. Usually, the best way to sort that out is by comparing sections to the DNA of one or both parents. But Ancestry developed a technique that uses the company\u2019s large DNA database \u2014 which includes 20 million people\u2019s genetic information \u2014 to find overlaps between each user and cousins or distant relatives also in the system. It uses those overlaps to sort each section of DNA by which parent it was inherited from.<\/p>\n

Ancestry was interested in developing a way to sort genetic information by parent for a while, Starr says, but it had to wait until the DNA database was big enough that the tool could be accurate. Now, with a database at the size it is now, Starr says Ancestry can have 95 percent precision for 90 percent of customers. \u201cThe bigger the database, the better you can do,\u201d he says. <\/p>\n

The database, though, is largely made up of people with European ancestry \u2014 the feature is less accurate for users who have other ancestry from other parts of the world, according to a scientific article from Ancestry describing the technique. The paper has not yet been peer-reviewed or published in a scientific journal. Blind spots around people of color are a longstanding bias<\/a> in genetic databases and genetic research more generally. DNA tests like Ancestry\u2019s that tie your genetics back to a particular ethnicity are also often criticized for giving people an incomplete picture<\/a> of what genetic heritage actually means and conflating ancestry with race.<\/p>\n

At first, the SideView feature will let customers see which side of the family various parts of their ethnicity came from. \u201cWhich side of the family did your German come from? Did your French come from? Et cetera,\u201d Starr says. Eventually, it\u2019ll allow people to see which side of the family any relatives identified through Ancestry are from. That\u2019ll make it easier for people to track family history and build out family trees, he says. <\/p>\n

The strategy Ancestry uses to divide genetic information by parental side could also help people understand more about their health and genetic risk factors, Starr says. For example, someone who has two copies of a certain gene from one parent might be at a higher risk of a disease than someone with two copies but one from each parent. Ancestry wouldn\u2019t do that work themselves \u2014 the company discontinued its health services in 2021<\/a>. But the company is publishing its results, and other groups could theoretically make use of that technique. <\/p>\n

\u201cThis opens up all sorts of avenues for additional features and research,\u201d Starr says. \u201cI think it\u2019s really exciting.\u201d<\/p>\n<\/div>\n


<\/br><\/code><\/p>\n

Source: https:\/\/www.theverge.com\/2022\/4\/13\/23021782\/ancestry-dna-sort-genes-parents-ethnicity<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Source: Consumer genetics and genealogy company Ancestry announced a new feature, called SideView, that will give customers information about which bits of their DNA \u2014 and which parts of their ethnicity \u2014 were inherited from each parent. 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