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\n

A preventable infection by a porcine virus might have contributed to the death of the first patient to have a heart transplant with a pig organ, MIT Technology Review <\/em>reported this week<\/a>.<\/p>\n
David Bennett Sr, who had severe heart disease, received a genetically modified pig heart in early January of this year \u2014 a major milestone in animal-to-human transplants, or xenotransplantation. He died in March<\/a>. Initially, the hospital where the procedure was performed said that the cause of death was unknown. <\/p>\n
But last month, Bennett\u2019s transplant surgeon said in a webinar<\/a> that the heart was infected with porcine cytomegalovirus, a virus that doesn\u2019t infect human cells but can damage the organ. Virus-free hearts transplanted into baboons survived much longer than virus-infected hearts, according to a German study.<\/a>  <\/p>\n
Bennett received a heart from biotechnology company Revivicor, which produces genetically modified pigs. They\u2019re supposed to be free of viruses, but this particular virus can be hard to detect, Joachim Denner, a virologist at the Free University of Berlin, told MIT Technology Review<\/em><\/a>. The company declined to comment to MIT Technology Review<\/em> about the heart and the virus. <\/p>\n
It\u2019s still unclear how big of a role the virus played in Bennett\u2019s death. But if he died because of the virus \u2014 and not because his body rejected the organ \u2014 groups working on xenotransplantation likely won\u2019t have to rethink their overall strategy. \u201cIf this was an infection, we can likely prevent it in the future,\u201d Bartley Griffith, the transplant surgeon, said during his presentation.<\/em><\/p>\n<\/div>\n

<\/br><\/code><\/p>\n
Source: https:\/\/www.theverge.com\/2022\/5\/6\/23060519\/pig-virus-heart-transplant-xenotransplantation<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Source: A preventable infection by a porcine virus might have contributed to the death of the first patient to have a heart transplant with a pig organ, MIT Technology Review reported this week. 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